Shares of Modena fell 4.4%, Pfizer fell 2%, Novavax fell nearly 1% and BioNTech fell 2.6%. The US Senate Finance Committee supported the nomination of "anti-vaccine" Kennedy Jr., the US health secretary.
The Nikkei 225 index continued its decline, falling nearly 3%.
The main contract for iron ore futures in Singapore fell nearly 3% to $98.2 a tonne.
Precious metal futures continued to decline, with the main contract of Shanghai Bank falling by nearly 2%, now reported at 7798 yuan/kg; the main contract of Shanghai Gold fell by nearly 1%, now reported at 623.08 yuan/gram.
Class A shares of securities firms weakened in the afternoon, the first venture fell nearly 6%, Zhongyuan Securities, Seawater Securities, Dongxing Securities, Cinda Securities, CITIC Construction Investment and so on fell.
Precious metal futures fell rapidly, with the main contract of Shanghai Bank falling by nearly 1% and now reporting 7885 yuan/kg; the main contract of Shanghai Gold narrowed its gain to 0.19% and now reporting 625.7 yuan/gram.
ICE's main sugar futures contract fell nearly 3% to 22.07 cents a pound.
The main contract of Consolidated European Line fell by nearly 7% and is now trading at 1,680 points.
Class A share Baijiu plate fell again, Kweichow Moutai fell nearly 2%, the total market value forced 1.60 trillion pass; rock shares sealed plate fell, Jinhui wine, Yilite, Shunxin agriculture, Tianyoude wine and so on fell more than 2%.
Ethereum fell to $2,300 per unit, a new low since August 5, and fell nearly 3% during the day.